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KMID : 0853020120150020121
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Journal of Korean Burn Society
2012 Volume.15 No. 2 p.121 ~ p.126
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Clinical Benefit of Cryoderm in Full Thickness Burns
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Kim Yonng-Min
Yang Hyeong-Tae
Yim Hae-Jun
Kim Do-Hern
Hur Jun
Kim Jong-Hyun
Cho Yong-Suk
Chun Wook
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Abstract
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Purpose: CryoDerm (CGbio) is derived donated human skin. After removing epidermis and fibroblast of dermal layer, it preserved with cryo-preservation technique using control rate freezer system. To prevent post burn joint contracture in massive burns, we have used CryoDerm in acute stage.
Methods: From January of 2010 to July of 2012, 50 patients who undergone CryoDerm graft with split thickness skin graft were reviewed. The operative method was as follows: 1) Early wound excision and or cadaveric allograft skin coverage was performed within 5 days after burn injury 2) 2∼3 weeks after wound excision, split thickness skin graft was performed with CryoDerm graft. Then graft take rate was investigated by inspection. Follow up duration was 3∼32 months.
Results: Mean age of patients was 42.2 (2∼70) years. Mean percentage of total body surface area burned was 27.22% (1∼61%). Among 50 patients, 98 joints was operated including 14 hands, 4 wrists, 10 shoulders, 23 elbows, 4 necks, 3 hip joints, 31 knee joints and 9 ankles and feet. Total used graft size of Cryoderm was 10,945 cm2. Average take rate was near 100%.
Conclusion: Cryoderm graft with split thickness skin graft can be used as a safe and effective operative method for one stage operation in acutely burned patients.
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KEYWORD
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CryoDerm, CGbio, Artificial dermis, Full thickness burns
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